Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 20/20 | 0.69 |
| ▸ | RARG | P13631 | 14/20 | 0.69 |
| ▸ | RARA | P10276 | 7/20 | 0.69 |
| ▸ | RARB | P10826 | 7/20 | 0.69 |
| ▸ | RXRB | P28702 | 6/20 | 0.69 |
| ▸ | RXRG | P48443 | 6/20 | 0.69 |
| ▸ | PPARG | P37231 | 10/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196030 | 1.00 | RXRA (0.69) | RXRARARGRARARARBRXRB | |
| SCHEMBL8588546 | 0.91 | RXRA (0.77) | RXRARARGRARARARBRXRB | |
| SCHEMBL8588550 | 0.91 | RXRA (0.77) | RXRARARGRARARARBRXRB | |
| SCHEMBL8588549 | 0.91 | RXRA (0.77) | RXRARARGRARARARBRXRB | |
| SCHEMBL502043 | 0.81 | RXRA (1.00) | RXRARARGRARARARBRXRB | |
| SCHEMBL5175957 | 0.81 | RXRA (1.00) | RXRARARGRARARARBRXRB | |
| SCHEMBL502044 | 0.81 | RXRA (1.00) | RXRARARGRARARARBRXRB | |
| SCHEMBL502045 | 0.81 | RXRA (1.00) | RXRARARGRARARARBRXRB | |
| SCHEMBL11485389 | 0.80 | RXRA (1.00) | RXRARARGRARARARBRXRB | |
| SCHEMBL6917258 | 0.80 | RXRA (0.46) | RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1336600-A2 | Dimer-selective RXR modulators and methods for their use | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2003-08-20 | — | — | EP | disclosed |