SCHEMBL502043

SCHEMBL502043

CCCOc1cc2c(cc1/C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC2(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RXRA P19793 20/20 1.00
RARG P13631 11/20 1.00
RXRB P28702 8/20 1.00
RXRG P48443 8/20 1.00
RARA P10276 7/20 1.00
RARB P10826 7/20 1.00
PPARG P37231 10/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL502044 1.00 RXRA (1.00) RXRARARGRXRBRXRGRARA
SCHEMBL5175957 1.00 RXRA (1.00) RXRARARGRXRBRXRGRARA
SCHEMBL502045 1.00 RXRA (1.00) RXRARARGRXRBRXRGRARA
SCHEMBL8899800 0.94 RXRA (0.88) RXRARARGRXRBRXRGRARA
SCHEMBL13752421 0.89 RXRA (0.81) RXRARARGRXRBRXRGRARA
SCHEMBL8568634 0.89 RXRA (0.80) RXRARARGRXRBRXRGRARA
SCHEMBL8568632 0.89 RXRA (0.80) RXRARARGRXRBRXRGRARA
SCHEMBL20646225 0.87 RXRA (0.77) RXRARARGRXRBRXRGRARA
SCHEMBL6344906 0.87 RXRA (0.77) RXRARARGRXRBRXRGRARA
SCHEMBL6344909 0.87 RXRA (0.77) RXRARARGRXRBRXRGRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12571046-B2 Methods of detecting and treating multiple system atrophy THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) 2026-03-10 US claimed
EP-3452041-B1 COMPOSITIONS AND METHODS FOR ADMINISTERING PPAR-GAMMA-AGONISTS, SURFACTANT PEPTIDES AND PHOSPHOLIPIDS LOS ANGELES BIOMEDICAL RES INST HARBOR UCLA MEDICAL CT (US) 2026-01-14 EP claimed
WO-2025024484-A1 COMPOSITIONS AND METHODS FOR TREATING BLOOD CANCER DUKE UNIVERSITY (US) 2025-01-30 WO claimed
US-20240398905-A1 COMPOSITIONS AND METHOD FOR ADMINISTERING PPARgamma AGONISTS, SURFACTANT PEPTIDES AND PHOSOPHOLIPIDS LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER 2024-12-05 US claimed
US-20240285540-A1 FUNCTIONAL THERAPEUTIC INDEX IN THE TREATMENT OF PERIPHERAL IMMUNE DYSFUNCTION MASCARENHAS DESMOND (US) 2024-08-29 US claimed
US-11951158-B2 Compositions and methods for administering PPARγ agonists, surfactant peptides and phospholipids LINDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER (US) 2024-04-09 US claimed
EP-4334436-A1 METHOD FOR INDUCING HYPERTROPHIC MUSCLE FIBERS FOR INDUSTRIAL MEAT PRODUCTION Yeda Research and Development Co. Ltd (IL) 2024-03-13 EP claimed
US-20240074473-A1 METHOD FOR INDUCING HYPERTROPHIC MUSCLE FIBERS FOR INDUSTRIAL MEAT PRODUCTION YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2024-03-07 US claimed
US-11642419-B2 Compositions and methods for treating cardiovascular related disorders THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-05-09 US claimed
WO-2022234586-A1 METHOD FOR INDUCING HYPERTROPHIC MUSCLE FIBERS FOR INDUSTRIAL MEAT PRODUCTION YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2022-11-10 WO claimed
EP-1621191-A1 Treatment of inflammatory diseases by RXR Antagonists Bollag, Werner (CH) 2006-02-01 EP claimed
EP-1612264-A1 ORGAN-FORMING METHOD Research Foundation Itsuu Laboratory (JP) 2006-01-04 EP claimed
JP-2005528088-A 2005-09-22 JP claimed
EP-1576089-A2 EXPANSION OF RENEWABLE STEM CELL POPULATIONS Gamida Cell Ltd. (IL) 2005-09-21 EP claimed
EP-1534820-A2 EX-VIVO EXPANSION OF HEMATOPOIETIC STEM CELL POPULATIONS IN MONONUCLEAR CELL CULTURES Gamida Cell Ltd. (IL) 2005-06-01 EP claimed
US-20050008624-A1 Expansion of renewable stem cell populations GAMIDA CELL LTD. 2005-01-13 US claimed
EP-1485464-A2 METHODS OF INDUCING DIFFERENTIATION IN EX VIVO EXPANDED STEM CELLS Gamida Cell Ltd. (IL) 2004-12-15 EP claimed
WO-2004016731-A2 EX-VIVO EXPANSION OF HEMATOPOIETIC STEM CELL POPULATIONS IN MONONUCLEAR CELL CULTURES GAMIDA-CELL LTD. (IL) 2004-02-26 WO claimed
WO-2003078567-A2 METHODS OF INDUCING DIFFERENTIATION IN EX VIVO EXPANDED STEM CELLS GAMIDA-CELL LTD. (IL) 2003-09-25 WO claimed
WO-2003062369-A2 EXPANSION OF RENEWABLE STEM CELL POPULATIONS GAMIDA-CELL LTD. (IL) 2003-07-31 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12571046-B2 Methods of detecting and treating multiple system atrophy SYNJ1, MYT1, SYNJ2 RXRA 18/4885RARG 382/4885RXRB 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.