SCHEMBL7196203

SCHEMBL7196203

CC1=Cc2c(ccc3ccccc23)C1[SiH3].CCC1=NC2=CC=C(C)C2=C1C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7201471 0.87
SCHEMBL9249191 0.76 ALDH1A1 (0.41) KDM4E
SCHEMBL7035971 0.74 KDM4E (0.32) KDM4E
SCHEMBL7776258 0.71
Hydrochloric Acid SCHEMBL6461445 0.69
SCHEMBL7197739 0.68 KDM4E (0.32) KDM4E
SCHEMBL7198796 0.64
SCHEMBL28529430 0.64 ALDH1A1 (0.36) KDM4E
Hydrochloric Acid SCHEMBL28529022 0.62 ALDH1A1 (0.34) KDM4E
SCHEMBL7037711 0.62 KDM4E (0.41) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6620953-B1 Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts BASSELL POLYOLEFINE GMBH (DE) 2003-09-16 US disclosed