Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 6/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187484 | 0.92 | ANPEP (0.59) | CYP1A2ANPEPHTR2AHRH1HTR2C | |
| SCHEMBL30633009 | 0.92 | ANPEP (0.59) | CYP1A2ANPEPHTR2AHRH1HTR2C | |
| SCHEMBL11144393 | 0.88 | CYP1A2 (0.58) | CYP1A2ANPEPCYP2A6HTR2AHRH1 | |
| SCHEMBL14169990 | 0.78 | ANPEP (0.47) | CYP1A2ANPEPHTR2A | |
| SCHEMBL9633656 | 0.75 | HTR2A (0.58) | ANPEPHTR2AHRH1HTR2CHDAC4 | |
| SCHEMBL948086 | 0.75 | ACP3 (0.46) | ANPEPCYP2A6HTR2AHRH1HTR2C | |
| SCHEMBL17070963 | 0.75 | ANPEP (0.57) | CYP1A2ANPEPHTR2AHRH1HTR2C | |
| SCHEMBL77106 | 0.74 | CYP1A2 (1.00) | CYP1A2ANPEPCYP2A6 | |
| SCHEMBL29366435 | 0.74 | CYP1A2 (1.00) | CYP1A2ANPEPCYP2A6 | |
| SCHEMBL22879299 | 0.74 | CYP1A2 (0.41) | CYP1A2ANPEPCYP2A6HTR2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668865-B1 | INDENYL COMPOUNDS AND CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | DSM NV (NL) | 2003-07-23 | — | — | EP | disclosed |
| US-5990253-A | METALLOCENES HAVING THE INDENE RING BINDING AT THE 2-POSITION RATHER THAN AT THE 1-POSITION; COORDINATION CATALYSTS; LESS CRYSTALLIZATION IN THE ADDITION POLYMERIZATION OF ELASTOMERS | DSM N.V. (NL) | 1999-11-23 | — | — | US | disclosed |
| US-5646322-A | Indenyl compounds and catalyst components for the polymerization of olefins | DSM N.V. (NL) | 1997-07-08 | — | — | US | disclosed |
| EP-0668865-A1 | INDENYL COMPOUNDS AND CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | DSM N.V. (NL) | 1995-08-30 | — | — | EP | disclosed |
| WO-1994011406-A1 | INDENYL COMPOUNDS AND CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | DSM N.V. (NL) | 1994-05-26 | — | — | WO | disclosed |