SCHEMBL9633656

SCHEMBL9633656

CC1c2ccccc2Cc2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 13/20 0.58
HRH1 P35367 9/20 0.52
HTR2C P28335 1/20 0.52
HDAC4 P56524 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45
ANPEP P15144 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11144393 0.86 CYP1A2 (0.58) HTR2AHRH1HTR2CHDAC4HDAC7
SCHEMBL8746509 0.84 HTR2A (0.52) HTR2AHRH1HTR2C
SCHEMBL13343950 0.82 HTR2A (0.43) HTR2AHRH1HTR2C
SCHEMBL18352989 0.81 HTR2A (0.45) HTR2AHRH1HTR2CANPEP
SCHEMBL2187484 0.81 ANPEP (0.59) HTR2AHRH1HTR2CHDAC4HDAC7
SCHEMBL30633009 0.81 ANPEP (0.59) HTR2AHRH1HTR2CHDAC4HDAC7
SCHEMBL22879435 0.80 BCHE (0.47) HTR2AHRH1ANPEP
SCHEMBL2600798 0.78 HTR2A (0.37) HTR2AHRH1HTR2C
SCHEMBL12401932 0.78 DRD2 (0.46) HTR2A
SCHEMBL18943757 0.78 HTR2A (0.47) HTR2AHRH1HTR2CANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991008190-A1 AMINO ACID PROTECTING GROUPS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-06-13 WO claimed
US-10685844-B2 Hardmask composition, method of forming pattern by using the hardmask composition, and hardmask formed using the hardmask composition SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-06-16 US disclosed
US-20190035635-A1 HARDMASK COMPOSITION, METHOD OF FORMING PATTERN BY USING THE HARDMASK COMPOSITION, AND HARDMASK FORMED USING THE HARDMASK COMPOSITION SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-01-31 US disclosed
US-5101059-A Xanthene compounds RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1992-03-31 US disclosed
WO-1991008190-A1 AMINO ACID PROTECTING GROUPS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-06-13 WO disclosed
US-4152356-A SELECTIVE CARBONYLATION OF 9,10-DIHYDROANTHRACENE TO FORM 9-FORMYL-9,10-DIHYDROANTHRACENE EXXON RESEARCH & ENGINEERING CO. (US) 1979-05-01 US disclosed
US-4131646-A Preparation of hydrogen peroxide from dihydroanthracene hydroperoxides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190035635-A1 HARDMASK COMPOSITION, METHOD OF FORMING PATTERN BY USING THE HARDMASK COMPOSITION, AND HARDMASK FORMED USING THE HARDMASK COMPOSITION DEK, HNRNPK, DGKA HTR2A 4854/4885HRH1 4021/4885HTR2C 4710/4885
US-10685844-B2 Hardmask composition, method of forming pattern by using the hardmask composition, and hardmask formed using the hardmask composition DEK, HNRNPK, DGKA HTR2A 4854/4885HRH1 4021/4885HTR2C 4710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.