Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.42 |
| ▸ | ABAT | P80404 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1760727 | 0.91 | ALDH1A1 (0.55) | ESR1ESR2ALDH1A1MAPTMEN1 | |
| SCHEMBL5507106 | 0.88 | ESR1 (0.44) | ESR1ESR2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL135213 | 0.84 | MAPT (0.60) | ESR1ESR2ALDH1A1MAPTHSD17B10 | |
| 4-Vinylphenol SCHEMBL28318354 | 0.83 | ALDH1A1 (0.50) | ESR1ESR2ALDH1A1MAPTALDH5A1 | |
| SCHEMBL9497107 | 0.82 | TP53 (0.47) | ESR1ESR2MAPTHSD17B10HTT | |
| Methane SCHEMBL10894585 | 0.82 | MAPT (0.57) | ESR1ESR2ALDH1A1MAPTHSD17B10 | |
| Ethane SCHEMBL3904717 | 0.82 | MAPT (0.57) | ESR1ESR2ALDH1A1MAPTHSD17B10 | |
| Hydrogen Peroxide SCHEMBL11347551 | 0.82 | MAPT (0.57) | ESR1ESR2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL28211191 | 0.82 | MAPT (0.57) | ESR1ESR2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL31482520 | 0.82 | MAPT (0.57) | ESR1ESR2ALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670420-B2 | A graft thermoplastic molding material comprising a copolymers of polycarbonate and an additional polymer with a hydroxy-containing compatibilizer; finely dispersed phase and resistance to phase separation | BAYER CORPORATION | 2003-12-30 | — | — | US | claimed |