SCHEMBL719637

SCHEMBL719637

BrC1=CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482644 0.90
SCHEMBL11515974 0.88 HDAC4 (0.38)
SCHEMBL11514017 0.88 HDAC4 (0.38)
SCHEMBL11515969 0.88 HDAC4 (0.38)
SCHEMBL11713017 0.88 HDAC4 (0.38)
SCHEMBL11513038 0.88 HDAC4 (0.38)
SCHEMBL11513040 0.88 HDAC4 (0.38)
SCHEMBL11515968 0.88 HDAC4 (0.38)
SCHEMBL2384838 0.88
SCHEMBL11513142 0.88 HDAC4 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114014869-B Chiral 2,2' -bipyridine ligand and preparation method and application thereof 西安交通大学 2023-03-24 CN claimed
CN-114014869-A Chiral 2,2' -bipyridine ligand and preparation method and application thereof 西安交通大学 2022-02-08 CN claimed
EP-3004120-B1 SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION UNIV NANYANG TECH (SG) 2018-08-29 EP claimed
US-20160136629-A1 SPIRO-1,1'-BINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALADIUM-CATALYZED ASYMMETRIC HECK REACTION NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-05-19 US claimed
EP-3004120-A1 SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION Nanyang Technological University (SG) 2016-04-13 EP claimed
WO-2014196930-A1 SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2014-12-11 WO claimed
EP-1594835-A4 METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES AUSPEX PHARMACEUTICALS INC (US) 2007-05-02 EP claimed
US-20060173199-A1 Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses HONG BORCHERNG 2006-08-03 US claimed
EP-1594835-A2 METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES Auspex Pharmaceuticals, Inc. (US) 2005-11-16 EP claimed
WO-2004064745-A2 METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES AUSPEX PHARMACEUTICALS, INC. (US) 2004-08-05 WO claimed
US-20020165411-A1 Sterically hindered phosphine ligands and uses thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-11-07 US claimed
WO-2002048160-A1 STERICALLY HINDERED PHOSPHINE LIGANDS AND USES THEREOF YALE UNIVERSITY (US) 2002-06-20 WO claimed
CN-121779218-A Preparation method of 3-bromo-2-cyclopentene-1-one 宿迁晨阳医药科技有限公司 2026-04-03 CN disclosed
CN-108368016-B Process for producing cyclopentyl alkyl ether compound 日本瑞翁株式会社 2023-09-26 CN disclosed
CN-114014869-B Chiral 2,2' -bipyridine ligand and preparation method and application thereof 西安交通大学 2023-03-24 CN disclosed
CN-114014869-A Chiral 2,2' -bipyridine ligand and preparation method and application thereof 西安交通大学 2022-02-08 CN disclosed
US-4138583-A ANTICOAGULANTS, CARDIOVASCULAR DISORDERS, HYPOTENSIVE AGENTS MILES LABORATORIES, INC. (US) 1979-02-06 US disclosed
US-4138582-A ANTICOAGULANTS, CARDIOVASCULAR DISORDERS, HYPOTENSIVE AGENTS MILES LABORATORIES, INC. (US) 1979-02-06 US disclosed
US-4066834-A Cycloalkenyl analogues of prostaglandins E MILES LABORATORIES, INC. (US) 1978-01-03 US disclosed
US-4031300-A High molecular weight, high unsaturation isobutylene-cyclopentadiene copolymers EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-06-21 US disclosed