Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199316 | 0.96 | ESR2 (0.48) | ESR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18100603 | 0.85 | ESR2 (0.39) | ESR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL504920 | 0.79 | FADS1 (0.39) | ESR2GRM2RIPK1 | |
| SCHEMBL3157843 | 0.78 | NPY5R (0.39) | GRM2NPY5RHCRTR2GRIA4 | |
| SCHEMBL7851951 | 0.78 | ESR2 (0.47) | ESR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL730107 | 0.77 | ESR2 (0.47) | ESR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6460962 | 0.75 | ESR2 (0.32) | ESR2NPY5R | |
| SCHEMBL6460965 | 0.75 | ESR2 (0.32) | ESR2NPY5R | |
| SCHEMBL745535 | 0.75 | ESR2 (0.64) | ESR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18284064 | 0.73 | GRIA4 (0.39) | ESR2GRM2NPY5RHCRTR2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103906727-B | There is the compound of 2-fluorophenyl oxygen methylmethane structure | DIC CORP. (JP) | 2015-11-25 | — | — | CN | disclosed |
| US-9181484-B2 | Compound having 2-fluorophenyloxymethane structure | DIC CORPORATION (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20150087847-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| US-8916718-B2 | Compound having 2-fluorophenyloxymethane structure | DIC CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| CN-103547555-B | Compound having 2-fluorophenyloxymethane structure | DAINIPPON INK & CHEMICALS | 2014-12-10 | — | — | CN | disclosed |
| US-20140275577-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |
| CN-103906727-A | Compound having 2-fluorophenyloxymethane structure | DAINIPPON INK & CHEMICALS | 2014-07-02 | — | — | CN | disclosed |
| CN-103547555-A | Compound having 2-fluorophenyloxymethane structure | DAINIPPON INK & CHEMICALS | 2014-01-29 | — | — | CN | disclosed |
| US-6599590-B2 | Unsaturated fluorine compound | CHISSO CORPORATION (JP) | 2003-07-29 | — | — | US | disclosed |
| US-20020015805-A1 | Fluoro-substituted alkenyl compounds, liquid crystal compositions, and liquid crystal display elements | CHISSO PETROCHEMICAL CORPORATION (JP) | 2002-02-07 | — | — | US | disclosed |
| EP-1158037-A1 | Fluoro-substitued alkenyl compounds, liquid crystal compositions, and liquid crystal display elements | CHISSO CORPORATION (JP) | 2001-11-28 | — | — | EP | disclosed |
| EP-0987238-A1 | LIQUID-CRYSTALLINE COMPOUNDS HAVING BICYCLO 1.1.1]PENTANE STRUCTURE, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 2000-03-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020015805-A1 | Fluoro-substituted alkenyl compounds, liquid crystal compositions, and liquid crystal display elements | YBX1, LEF1, YBX3 | ESR2 2948/4885PDE4A 4634/4885PDE4B 4540/4885 |
| US-20140275577-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | PIK3CD, TEC, PIK3C3 | ESR2 2052/4885PDE4A 1162/4885PDE4B 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.