Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PRKCA | P17252 | 14/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196527 | 0.92 | TSHR (0.36) | TSHRPRKCAPRKCDALDH1A1 | |
| SCHEMBL7192883 | 0.87 | ALDH1A1 (0.36) | TSHRPRKCAPRKCDALDH1A1 | |
| SCHEMBL15557466 | 0.83 | TSHR (0.49) | TSHRPRKCAPRKCDALDH1A1 | |
| SCHEMBL7200430 | 0.75 | ALDH1A1 (0.38) | TSHRALDH1A1 | |
| SCHEMBL2883101 | 0.75 | TSHR (0.43) | TSHRPRKCAPRKCDALDH1A1SIRT2 | |
| SCHEMBL3286712 | 0.74 | TSHR (0.43) | TSHRALDH1A1 | |
| SCHEMBL2882617 | 0.72 | TSHR (0.46) | TSHRPRKCAALDH1A1 | |
| SCHEMBL8588553 | 0.72 | ALDH1A1 (0.38) | TSHRPRKCAALDH1A1 | |
| SCHEMBL7872075 | 0.72 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL9282633 | 0.72 | ALDH1A1 (0.40) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735118-B1 | POWDER COATING RESIN COMPOSITION | DOW CORNING TORAY SILICONE (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6090890-A | EPOXY-FUNCTIONAL BRANCHED ORGANOPOLYSILOXANE AND AN ACRYLIC RESIN CONTAINING AROMATIC VINYL MONOMERIC UNITS IN AN AMOUNT OF FROM 5 TO 70 WT %, AND FLUORORESINS, SAID COMPOUND BEARING A FUNCTIONAL GROUP REACTIVE WITH THE EPOXY GROUP | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0735118-A1 | POWDER COATING RESIN COMPOSITION | Dow Corning Toray Silicone Co., Ltd. (JP) | 1996-10-02 | — | — | EP | disclosed |