SCHEMBL7200430

SCHEMBL7200430

C=C(C)C(=O)OCC1(C)COC(=O)O1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TSHR P16473 3/20 0.35
THRB P10828 1/20 0.33
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9404102 0.85 ALDH1A1 (0.36) ALDH1A1TSHRTHRB
SCHEMBL9282633 0.81 ALDH1A1 (0.40) ALDH1A1TSHRTHRBATM
SCHEMBL714093 0.80 TSHR (0.48) ALDH1A1TSHRTHRB
SCHEMBL15274791 0.80 ALDH1A1 (0.41) ALDH1A1TSHRTHRB
SCHEMBL7192883 0.79 ALDH1A1 (0.36) ALDH1A1TSHRTHRBATM
SCHEMBL9246851 0.79 TSHR (0.35) ALDH1A1TSHRATM
SCHEMBL7872075 0.78 ALDH1A1 (0.36) ALDH1A1TSHRTHRB
SCHEMBL7196527 0.77 TSHR (0.36) ALDH1A1TSHRTHRBATM
SCHEMBL8588553 0.76 ALDH1A1 (0.38) ALDH1A1TSHRTHRBATM
SCHEMBL7196483 0.75 TSHR (0.40) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2325695-B1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORP (JP) 2017-12-20 EP disclosed
US-20110223537-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND POLYMER JSR CORPORATION (JP) 2011-09-15 US disclosed
US-20110223537-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND POLYMER JSR CORPORATION (JP) 2011-09-15 US disclosed
EP-2325695-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2011-05-25 EP disclosed
EP-0735118-B1 POWDER COATING RESIN COMPOSITION DOW CORNING TORAY SILICONE (JP) 2003-07-23 EP disclosed
US-6090890-A EPOXY-FUNCTIONAL BRANCHED ORGANOPOLYSILOXANE AND AN ACRYLIC RESIN CONTAINING AROMATIC VINYL MONOMERIC UNITS IN AN AMOUNT OF FROM 5 TO 70 WT %, AND FLUORORESINS, SAID COMPOUND BEARING A FUNCTIONAL GROUP REACTIVE WITH THE EPOXY GROUP DOW CORNING TORAY SILICONE CO., LTD. (JP) 2000-07-18 US disclosed
EP-0735118-A1 POWDER COATING RESIN COMPOSITION Dow Corning Toray Silicone Co., Ltd. (JP) 1996-10-02 EP disclosed