Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.44 |
| ▸ | HTR1B | P28222 | 6/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198186 | 0.92 | HTR1A (0.43) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL7201893 | 0.89 | MEN1 (0.44) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL7198636 | 0.81 | KDM4E (0.49) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL7203216 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7199734 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7197966 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7203222 | 0.74 | KDM4E (0.51) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL7198955 | 0.73 | KDM4E (0.50) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL7198212 | 0.73 | KDM4E (0.51) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL7202148 | 0.70 | KDM4E (0.49) | HTR1AADRA1DHTR1BADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323719-A1 | Thienopyrimidine compounds and salts thereof and process for the preparation of the same | NIPPON SODA CO., LTD. (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6482948-B1 | Thienopyrimidine compounds and salts thereof and process for the preparation of the same | NIPPON SODA CO., LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| EP-1167367-A1 | THIENOPYRIMIDINE COMPOUNDS AND SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | NIPPON SODA CO., LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |