Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.41 |
| ▸ | HTR1B | P28222 | 4/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198186 | 0.90 | HTR1A (0.43) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7196485 | 0.89 | HTR1A (0.44) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7197966 | 0.88 | KDM4E (0.47) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7198636 | 0.79 | KDM4E (0.49) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7202472 | 0.79 | KDM4E (0.51) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7203216 | 0.77 | KDM4E (0.51) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7199734 | 0.74 | KDM4E (0.47) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL27377291 | 0.73 | MEN1 (0.42) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL27531812 | 0.72 | MEN1 (0.42) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7203222 | 0.72 | KDM4E (0.51) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323719-A1 | Thienopyrimidine compounds and salts thereof and process for the preparation of the same | NIPPON SODA CO., LTD. (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6482948-B1 | Thienopyrimidine compounds and salts thereof and process for the preparation of the same | NIPPON SODA CO., LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| EP-1167367-A1 | THIENOPYRIMIDINE COMPOUNDS AND SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | NIPPON SODA CO., LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |