Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028841 | 0.89 | AKT1 (0.40) | TDP1GAAALDH1A1NOS3NOS1 | |
| SCHEMBL28433525 | 0.87 | AKT1 (0.40) | TDP1GAAALDH1A1NOS3NOS1 | |
| SCHEMBL5372205 | 0.84 | TDP1 (0.40) | TDP1GAAALDH1A1NOS3NOS1 | |
| SCHEMBL22259472 | 0.81 | ALDH1A1 (0.42) | ALDH1A1NOS3NOS1NOS2KEAP1 | |
| SCHEMBL5388711 | 0.81 | ALDH1A1 (0.43) | TDP1GAAALDH1A1NOS3NOS1 | |
| SCHEMBL28097911 | 0.81 | PRKCI (0.37) | GAAALDH1A1CASP1PRKCIACHE | |
| SCHEMBL27309641 | 0.81 | TDP1 (0.38) | TDP1GAAALDH1A1NOS3NOS1 | |
| SCHEMBL14434428 | 0.81 | PRKCI (0.53) | TDP1GAAALDH1A1CASP1PRKCI | |
| SCHEMBL10952738 | 0.80 | CASP1 (0.40) | TDP1GAAALDH1A1CASP1PRKCI | |
| SCHEMBL2339661 | 0.79 | MAPT (0.41) | TDP1GAAALDH1A1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104817459-B | The method for generating cyclic aliphatic two-and polyamines for Hydrogenated aromatic two-and polyamines | 科思创德国股份有限公司 | 2019-03-08 | — | — | CN | claimed |
| WO-2022090523-A1 | CHIRAL POLYMERS AND USE THEREOF | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2022-05-05 | — | — | WO | disclosed |
| CN-1217808-C | Inflated tyre with double layer structure outer tyre surface | SUMITOMO RUBBER IND (JP) | 2005-09-07 | — | — | CN | disclosed |
| CN-1425573-A | Inflated tyre with double layer structure outer tyre surface | SUMITOMO RUBBER IND (JP) | 2003-06-25 | — | — | CN | disclosed |
| EP-0676443-B1 | Silica filled rubbery vulcanizates | BAYER INC (CA) | 2003-03-05 | — | — | EP | disclosed |
| US-5693712-A | SHAPING AND VULCANIZING MIXTURE OF RUBBERY POLYMER HAVING TWO OR THREE DOMAINS AND ONE OF BUTADIENE-STYRENE COPOLYMER, SILICA FILLER, POLYSULFIDE SILANE COMPOUND, AND SULFUR VULCANIZING AGENT | BAYER INC. (CA) | 1997-12-02 | — | — | US | disclosed |
| EP-0676443-A2 | Silica filled rubbery vulcanizates | BAYER RUBBER INC. (CA) | 1995-10-11 | — | — | EP | disclosed |