Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | CPA3 | P15088 | 1/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRND | Q07001 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL1921535 | 0.91 | SLC7A5 (0.49) | SLC7A5ITGB3ITGA2BALPIPKM | |
| Tyrosine SCHEMBL1921492 | 0.90 | SLC7A5 (0.48) | SLC7A5ITGB3ITGA2BALPIPKM | |
| Tyrosine SCHEMBL6460601 | 0.90 | SLC7A5 (0.50) | SLC7A5ITGB3ITGA2BALPIPKM | |
| Tyrosine SCHEMBL2723437 | 0.89 | SLC7A5 (0.57) | SLC7A5ITGB3ITGA2BALPIPKM | |
| Tyrosine SCHEMBL29062530 | 0.89 | SLC7A5 (0.63) | SLC7A5ITGB3ITGA2BALPIPKM | |
| Tyrosine SCHEMBL1696965 | 0.89 | SLC7A5 (0.63) | SLC7A5ITGB3ITGA2BALPIPKM | |
| Tyrosine SCHEMBL1921644 | 0.88 | SLC7A5 (0.51) | SLC7A5ITGB3ITGA2BALPIPKM | |
| Tyrosine SCHEMBL10720154 | 0.88 | THRB (0.41) | SLC7A5ITGB3ITGA2BALPIPKM | |
| Tyrosine SCHEMBL22654492 | 0.87 | SLC7A5 (0.67) | SLC7A5ITGB3ITGA2BALPIPKM | |
| Tyrosine SCHEMBL27074660 | 0.87 | SLC7A5 (0.67) | SLC7A5ITGB3ITGA2BALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030027752-A1 | Leucine-based motif and clostridial neurotoxins | ALLERGAN SALES, INC. | 2003-02-06 | — | — | US | disclosed |