Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366887 | 0.82 | HTR1B (0.46) | HTR1BKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL1127659 | 0.82 | HTR1B (0.46) | HTR1BKDM4EALDH1A1HPGDTDP1 | |
| Oxirane SCHEMBL28066237 | 0.74 | HPGD (0.50) | HTR1BKDM4EALDH1A1HPGDATM | |
| SCHEMBL4371294 | 0.71 | HPGD (0.56) | HTR1BKDM4EALDH1A1HPGDATM | |
| SCHEMBL11331791 | 0.71 | HTR1B (0.47) | HTR1BKDM4EALDH1A1HPGDTDP1 | |
| Ethylene SCHEMBL3362752 | 0.70 | HPGD (0.55) | HTR1BKDM4EALDH1A1HPGDATM | |
| Water SCHEMBL21694712 | 0.70 | HPGD (0.55) | HTR1BKDM4EALDH1A1HPGDATM | |
| SCHEMBL21089714 | 0.69 | TSHR (0.39) | PDE9AKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL30800894 | 0.68 | HTR1B (0.61) | HTR1BKDM4EALDH1A1HPGDATM | |
| SCHEMBL27683986 | 0.67 | HTR1B (0.44) | HTR1BKDM4EALDH1A1HPGDKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069120-B1 | Naphthalene derivative, binaphthalene derivative and biphenyl derivative and cationically curable compound | TOAGOSEI CO LTD (JP) | 2003-08-13 | — | — | EP | claimed |
| US-6469108-B2 | REACTING A DIHYDROXYNAPHTHALENE WITH 3-ALKYL-3-CHLOROMETHYLOXETANE OR 3-CHLOROMETHYLOXETANE IN PRESENCE OF ALKALI METAL HYDROXIDE, ALKALI METAL HYDRIDE OR ALKALI METAL | TOAGOSEI CO., LTD. (JP) | 2002-10-22 | — | — | US | claimed |
| US-20020103330-A1 | Naphthalene derivative, binaphthalene derivative and biphenyl derivative and cationically curable compound | TOAGOSEI CO., LTD. | 2002-08-01 | — | — | US | claimed |
| EP-1069120-A1 | Naphthalene derivative, binaphthalene derivative and biphenyl derivative and cationically curable compound | TOAGOSEI CO., LTD. (JP) | 2001-01-17 | — | — | EP | claimed |
| EP-1069120-B1 | Naphthalene derivative, binaphthalene derivative and biphenyl derivative and cationically curable compound | TOAGOSEI CO LTD (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-6469108-B2 | REACTING A DIHYDROXYNAPHTHALENE WITH 3-ALKYL-3-CHLOROMETHYLOXETANE OR 3-CHLOROMETHYLOXETANE IN PRESENCE OF ALKALI METAL HYDROXIDE, ALKALI METAL HYDRIDE OR ALKALI METAL | TOAGOSEI CO., LTD. (JP) | 2002-10-22 | — | — | US | disclosed |
| US-20020103330-A1 | Naphthalene derivative, binaphthalene derivative and biphenyl derivative and cationically curable compound | TOAGOSEI CO., LTD. | 2002-08-01 | — | — | US | disclosed |
| US-6365760-B1 | BIS(3-ALKYLOXETAN-3-YL)-METHOXY)BIPHENYL COMPOUNDS USED AS OPTICAL MATERIALS; WORKABILITY; LOW VISCOSITY; HIGH REFRACTIVE INDEX; PHOTO AND THERMOCURING; | TOAGOSEI CO., LTD. (JP) | 2002-04-02 | — | — | US | disclosed |
| JP-2001040085-A | CATION CURABLE COMPOSITION | TOAGOSEI CO LTD | 2001-02-13 | — | — | JP | disclosed |
| EP-1069120-A1 | Naphthalene derivative, binaphthalene derivative and biphenyl derivative and cationically curable compound | TOAGOSEI CO., LTD. (JP) | 2001-01-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103330-A1 | Naphthalene derivative, binaphthalene derivative and biphenyl derivative and cationically curable compound | NDC1, BECN1, NUCB2 | PDE9A 4678/4885HTR1B 1933/4885KDM4E 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.