Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | IAPP | P10997 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200650 | 0.85 | IAPP (0.51) | HSD17B10CYP3A4NFKB1HIF1ACYP2D6 | |
| SCHEMBL7198063 | 0.85 | ESR1 (0.60) | HSD17B10CYP3A4HIF1ADRD2DRD3 | |
| SCHEMBL7196489 | 0.85 | ESR1 (0.60) | HSD17B10CYP3A4HIF1ADRD2DRD3 | |
| SCHEMBL6938226 | 0.83 | TRPV1 (0.49) | HSD17B10CYP3A4NFKB1HIF1ACYP2D6 | |
| SCHEMBL8389380 | 0.83 | OPRK1 (0.62) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL9350008 | 0.82 | IAPP (0.61) | HSD17B10CYP3A4NFKB1HIF1ACYP2D6 | |
| SCHEMBL7197929 | 0.80 | ALDH1A1 (0.67) | HSD17B10CYP3A4HIF1AMAPTMEN1 | |
| SCHEMBL7271371 | 0.80 | ESR1 (0.62) | HSD17B10CYP3A4HIF1ATRPV1MAPT | |
| SCHEMBL7193347 | 0.80 | ALDH1A1 (0.67) | HSD17B10CYP3A4HIF1AMAPTMEN1 | |
| SCHEMBL7271343 | 0.80 | ESR1 (0.62) | HSD17B10CYP3A4HIF1ATRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596669-B1 | Comprising a support and two reversible heat-sensitive recording layers having different colors formed on the same side of the support, comprising colorless electron-donative dye precursor and an electron-accepting compound | MITSUBISHI PAPER MILLS LIMITED (JP) | 2003-07-22 | — | — | US | disclosed |
| US-6004899-A | SURFACE TREATED WITH SILANE, TITANATE, AND/OR ALUMINUM COUPLING AGENT; PIGMENT; ERASIBILITY | MITSUBISHI PAPER MILLS LIMITED (JP) | 1999-12-21 | — | — | US | disclosed |