SCHEMBL7197984

SCHEMBL7197984

CC(C)CC1=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc2C1CCC1C(CC(C)C)=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6890535 0.86 BRD4 (0.35) BRD4CREBBP
SCHEMBL7200922 0.85 ADORA3 (0.32)
SCHEMBL7037709 0.84 BRD4 (0.34) BRD4CREBBP
SCHEMBL7035230 0.83 NPC1 (0.32) BRD4CREBBP
SCHEMBL6892645 0.82 BRD4 (0.34) BRD4CREBBP
Hydrochloric Acid SCHEMBL5691814 0.82 BRD4 (0.30) BRD4CREBBP
SCHEMBL6890554 0.80 BRD4 (0.36) BRD4CREBBP
Hydrochloric Acid SCHEMBL6893542 0.80 BRD4 (0.31) BRD4CREBBP
Hydrochloric Acid SCHEMBL6895136 0.80 BRD4 (0.31) BRD4CREBBP
Hydrochloric Acid SCHEMBL6229957 0.80 BRD4 (0.31) BRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6620953-B1 Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts BASSELL POLYOLEFINE GMBH (DE) 2003-09-16 US disclosed