Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197984 | 0.85 | BRD4 (0.33) | — | |
| SCHEMBL4620494 | 0.84 | PDCD1 (0.33) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL27478887 | 0.82 | ADORA3 (0.31) | ADORA3ADORA2AADORA2BADORA1PDCD1 | |
| Hydrochloric Acid SCHEMBL5951936 | 0.81 | ADORA3 (0.33) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL27524733 | 0.80 | — | — | |
| SCHEMBL5951939 | 0.80 | — | — | |
| SCHEMBL7034781 | 0.79 | PDCD1 (0.33) | PDCD1CD274KMT2ACHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL4660358 | 0.79 | — | — | |
| SCHEMBL1240065 | 0.79 | — | — | |
| SCHEMBL5953053 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620953-B1 | Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts | BASSELL POLYOLEFINE GMBH (DE) | 2003-09-16 | — | — | US | disclosed |