Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555487 | 0.91 | CA2 (0.35) | CA2CA9CA12CA1CA7 | |
| Ethylene Glycol SCHEMBL9640698 | 0.89 | TSHR (0.33) | CA2CA9TSHR | |
| Allylamine SCHEMBL17510059 | 0.87 | ALDH1A1 (0.41) | CA2CA9ALDH1A1CA12CA1 | |
| Hydrazine SCHEMBL16102609 | 0.87 | CA2 (0.38) | CA2CA9CA12CA1CA7 | |
| Hydroxyamine SCHEMBL9307543 | 0.87 | CA2 (0.38) | CA2CA9CA12CA1CA7 | |
| SCHEMBL29655 | 0.87 | — | — | |
| SCHEMBL28900865 | 0.87 | CA2 (0.36) | CA2CA9TSHRCA12CA1 | |
| SCHEMBL15349414 | 0.87 | CA2 (0.36) | CA2CA9TSHRCA12CA1 | |
| Allyl Alcohol SCHEMBL27620579 | 0.85 | TSHR (0.43) | CA2CA9TSHR | |
| Methylamine SCHEMBL2059698 | 0.85 | CA2 (0.37) | CA2CA9TSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253489-B1 | ANTIDANDRUFF SHAMPOO COMPOSITION HAVING IMPROVED SUSPENSION PROPERTIES | HELENE CURTIS, INC. (US) | 1993-03-10 | — | — | EP | claimed |
| US-5154847-A | Liquid carrier with anionic surfactant, antidandruff agent, suspending alkanolamide or wax ester, crosslinked neutralized polyacrylic acid; stability | HELENE CURTIS, INC. (US) | 1992-10-13 | — | — | US | claimed |
| EP-0329376-A2 | Polymeric films | COURTAULDS FILMS & PACKAGING (HOLDINGS) LTD. (GB) | 1989-08-23 | — | — | EP | claimed |
| US-4830774-A | BLEND WITH CROSSLINKED ETHYLENE-MALEIC ANHYDRIDE COPOLYMER | HELENE CURTIS, INC. (US) | 1989-05-16 | — | — | US | claimed |
| EP-2964741-A1 | A METHOD OF PREPARING ANHYDROUS ALKYL (ETHOXY) SULPHATE COMPOSITIONS | Zschimmer & Schwarz Italiana S.p.A. (IT) | 2016-01-13 | — | — | EP | disclosed |
| CN-104245781-A | Enhancing antimicrobial activity of biocides with polymers | BASF SE | 2014-12-24 | — | — | CN | disclosed |
| WO-2014136091-A1 | A METHOD OF PREPARING ANHYDROUS ALKYL (ETHOXY) SULPHATE COMPOSITIONS | ZSCHIMMER & SCHWARZ ITALIANA S.P.A. (IT) | 2014-09-12 | — | — | WO | disclosed |
| US-6593318-B2 | Oral administering | PHARMACEUTICAL RESOURCES INC. | 2003-07-15 | — | — | US | disclosed |
| US-6593320-B2 | Stability; oral administering; anticancer agents | PHARMACEUTICAL RESOURCES INC. | 2003-07-15 | — | — | US | disclosed |
| US-20020173497-A1 | Flocculated suspension of megestrol acetate | PHARMACEUTICAL RESOURCES, INC. | 2002-11-21 | — | — | US | disclosed |
| US-20020028794-A1 | Aqueous suspension; dietetics | ROXANE LABORATORIES, INC. | 2002-03-07 | — | — | US | disclosed |
| US-20010048931-A1 | Flocculated suspension of megestrol acetate | PHARMACEUTICAL RESOURCES INC. | 2001-12-06 | — | — | US | disclosed |
| WO-1996001311-A1 | BLEACHING COMPOSITIONS | WARWICK INTERNATIONAL GROUP LIMITED (GB) | 1996-01-18 | — | — | WO | disclosed |
| WO-1996001309-A1 | BLEACHING COMPOSITIONS | WARWICK INTERNATIONAL GROUP LIMITED (GB) | 1996-01-18 | — | — | WO | disclosed |
| WO-1995021236-A1 | HARD SURFACE CLEANER CONTAINING OXIDISING COMPOSITION | WARWICK INTERNATIONAL GROUP LIMITED (GB) | 1995-08-10 | — | — | WO | disclosed |
| US-5286272-A | FREE-FLOWING | OMS INVESTMENTS, INC. | 1994-02-15 | — | — | US | disclosed |
| EP-0329376-A3 | POLYMERIC FILMS | COURTAULDS FILMS & PACKAGING (HOLDINGS) LTD. (GB) | 1990-06-13 | — | — | EP | disclosed |
| EP-0329376-A2 | Polymeric films | COURTAULDS FILMS & PACKAGING (HOLDINGS) LTD. (GB) | 1989-08-23 | — | — | EP | disclosed |
| US-4772308-A | FREE-FLOWING, AMMONIUM-CONTAINING FERTILIZERS; ALKYL SULFATE ADDITIVES | INTEVEP, S.A. (VE) | 1988-09-20 | — | — | US | disclosed |
| US-4772308-A | FREE-FLOWING, AMMONIUM-CONTAINING FERTILIZERS; ALKYL SULFATE ADDITIVES | INTEVEP, S.A. (VE) | 1988-09-20 | — | — | US | disclosed |