SCHEMBL7198249 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	CA1	P00915	1/20	0.41

▸	CA2	P00918	1/20	0.41

▸	APLNR	P35414	1/20	0.40

▸	LDHA	P00338	1/20	0.40

▸	TBXAS1	P24557	11/20	0.38

▸	HDAC4	P56524	1/20	0.38

▸	HDAC6	Q9UBN7	1/20	0.38

▸	NPC1	O15118	1/20	0.37

▸	POLB	P06746	1/20	0.37

▸	RAB9A	P51151	1/20	0.37

▸	SMN1; SMN2	Q16637	1/20	0.37

▸	MMP2	P08253	1/20	0.36

▸	MMP3	P08254	1/20	0.36

▸	ATM	Q13315	1/20	0.36

▸	KMT2A	Q03164	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7199332	1.00	CA1 (0.41)	CA1CA2APLNRLDHATBXAS1
SCHEMBL7192273	0.86	CA1 (0.38)	CA1CA2APLNRTBXAS1HDAC4
SCHEMBL3953584	0.86	TBXAS1 (0.43)	CA1CA2APLNRLDHATBXAS1
SCHEMBL7192269	0.86	CA1 (0.37)	CA1CA2APLNRTBXAS1HDAC4
SCHEMBL4848914	0.85	CA1 (0.44)	CA1CA2APLNRTBXAS1HDAC4
SCHEMBL14424972	0.85	CA1 (0.37)	CA1CA2APLNRTBXAS1HDAC4
SCHEMBL14424945	0.85	CA1 (0.37)	CA1CA2APLNRTBXAS1HDAC4
SCHEMBL6817267	0.84	CA1 (0.43)	CA1CA2LDHATBXAS1NPC1
SCHEMBL6818117	0.84	CA1 (0.43)	CA1CA2LDHATBXAS1NPC1
SCHEMBL7096896	0.83	CA1 (0.40)	CA1CA2APLNRTBXAS1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2003080567-A2	INTERMEDIATES FOR THE SYNTHESIS OF DISCODERMOLIDE AND RELATED ANALOGUES AND METHODS FOR THEIR PREPARATION	NOVARTIS AG (CH)	2003-10-02	—	—	WO	disclosed