Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2725195 | 0.83 | ACE2 (0.46) | ACE2KDM4EPTPN1MYCTSHR | |
| SCHEMBL1298535 | 0.82 | ACE2 (0.44) | ACE2KDM4EPTPN1PTPN11MYC | |
| SCHEMBL21143412 | 0.80 | ACE2 (0.43) | ACE2KDM4EPTPN1PTPN11MYC | |
| SCHEMBL21143417 | 0.79 | ACE2 (0.43) | ACE2KDM4EPTPN1PTPN11MYC | |
| SCHEMBL1683567 | 0.78 | ACE2 (0.45) | ACE2KDM4EPTPN1PTPN11MYC | |
| SCHEMBL815099 | 0.77 | ACE2 (0.51) | ACE2KDM4EPTPN1MYCRARB | |
| SCHEMBL5685962 | 0.76 | ACE2 (0.45) | ACE2KDM4EPTPN11MYCTSHR | |
| SCHEMBL7523843 | 0.75 | ACE2 (0.44) | ACE2PTPN11MAPK1RARBTSHR | |
| SCHEMBL4541962 | 0.73 | ACE2 (0.40) | ACE2KDM4EMAPK1RARBTSHR | |
| SCHEMBL7524968 | 0.72 | ACE2 (0.47) | ACE2KDM4EMYCTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620883-B2 | Thermoplastic resins | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-16 | — | — | US | disclosed |
| US-6509402-B1 | Compositions with improved properties based on optionally rubber-modified polymers of vinyl aromatics, e.g. styrene and/ or alpha -methyl styrene and acrylonitrile and/or acrylates, which contain a special acid-reacting polyether as the | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-21 | — | — | US | disclosed |