Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Drometrizole SCHEMBL1937812 | 0.94 | NPC1 (0.64) | NPC1RAB9ALMNATSHRCYP1A2 | |
| SCHEMBL29350736 | 0.92 | NPC1 (0.49) | NPC1RAB9ALMNATSHRCYP1A2 | |
| SCHEMBL29708 | 0.92 | NPC1 (0.49) | NPC1RAB9ALMNATSHRCYP1A2 | |
| SCHEMBL22372500 | 0.91 | NPC1 (0.44) | NPC1RAB9ALMNATSHRCYP1A2 | |
| SCHEMBL78159 | 0.89 | NPC1 (0.64) | NPC1RAB9ALMNATSHRPOLB | |
| SCHEMBL29354646 | 0.89 | NPC1 (0.64) | NPC1RAB9ALMNATSHRPOLB | |
| SCHEMBL712969 | 0.87 | NPC1 (0.38) | NPC1RAB9ALMNATSHRCYP1A2 | |
| SCHEMBL29706577 | 0.87 | NPC1 (0.38) | NPC1RAB9ALMNATSHRCYP1A2 | |
| Drometrizole SCHEMBL16212519 | 0.84 | NPC1 (0.56) | NPC1RAB9ALMNATSHRCYP1A2 | |
| Bumetrizole SCHEMBL3740116 | 0.84 | NPC1 (0.50) | NPC1RAB9ALMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313565-B | Polymerizable composition for optical member | 豪雅镜片泰国有限公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-109843958-B | Method for producing resin for optical member, spectacle lens, and spectacles | 豪雅镜片泰国有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-113165359-A | Acrylic films with improved UV protection | 罗姆化学有限责任公司 | 2021-07-23 | — | — | CN | disclosed |
| US-6593434-B1 | Condensation polymerization, esterification, melt mixing or kneading; high molecular weight, low crystallinity | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |