Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22372500 | 0.93 | NPC1 (0.44) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| Bumetrizole SCHEMBL5353195 | 0.93 | NPC1 (0.60) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| Drometrizole SCHEMBL16212519 | 0.92 | NPC1 (0.56) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| Bumetrizole SCHEMBL8250511 | 0.92 | NPC1 (0.54) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| Octrizole SCHEMBL8599630 | 0.91 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| Bumetrizole SCHEMBL6068328 | 0.91 | NPC1 (0.60) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| Bumetrizole SCHEMBL5194149 | 0.88 | NPC1 (0.48) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| Bumetrizole SCHEMBL8603228 | 0.87 | NPC1 (0.53) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| Bumetrizole SCHEMBL2398487 | 0.87 | NPC1 (0.53) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| Bumetrizole SCHEMBL23734 | 0.87 | NPC1 (0.53) | NPC1RAB9ALMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816424-B2 | Biodegradable plastics composition, molded article of the composition, and method of controlling biodegradation rate | NISSHINBO INDUSTRIES, INC. (JP) | 2010-10-19 | — | — | US | disclosed |