Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | TYR | P14679 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30800911 | 0.93 | ALOX5 (0.49) | ALOX15MAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL29180392 | 0.93 | ALOX5 (0.49) | ALOX15MAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10067473 | 0.93 | ALOX5 (0.49) | ALOX15MAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL30604741 | 0.93 | ALOX15 (0.56) | ALOX15MAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL3408192 | 0.93 | ALOX15 (0.56) | ALOX15MAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL11512116 | 0.91 | ALOX5 (0.50) | ALOX15MAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8749642 | 0.90 | ALOX15 (0.53) | ALOX15MAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL12733100 | 0.90 | ALOX15 (0.53) | ALOX15MAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9850166 | 0.90 | ALOX15 (0.53) | ALOX15MAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9142981 | 0.87 | ALOX5 (0.46) | ALOX15MAPTKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596672-B1 | A calcium, barium, or strontium overbased acidic material in an amount to contribute 0.01 to 0.79 percent sulfated ash; a magnesium or sodium overbased acidic material in an amount to contribute 0.01 to 0.79 percent sulfated ash | THE LUBRIZOL CORPORATION | 2003-07-22 | — | — | US | disclosed |
| EP-0725129-B1 | Low ash lubricant compositions | LUBRIZOL CORP (US) | 2001-12-12 | — | — | EP | disclosed |