Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 13/20 | 0.54 |
| ▸ | PDE5A | O76074 | 4/20 | 0.46 |
| ▸ | PDE6D | O43924 | 1/20 | 0.44 |
| ▸ | PDE6A | P16499 | 1/20 | 0.44 |
| ▸ | PDE6G | P18545 | 1/20 | 0.44 |
| ▸ | PDE6B | P35913 | 1/20 | 0.44 |
| ▸ | PDE6C | P51160 | 1/20 | 0.44 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195650 | 0.93 | PRKCI (0.47) | PRKCIKDM4EALDH1A1GAAMAPT | |
| SCHEMBL5780971 | 0.86 | KDM4E (0.54) | PRKCIKDM4EALDH1A1GAAMAPT | |
| SCHEMBL7169369 | 0.83 | KDM4E (0.51) | PRKCIKDM4EALDH1A1GAAMAPT | |
| SCHEMBL7197493 | 0.83 | KDM4E (0.44) | PRKCIPDE5AKDM4EALDH1A1GAA | |
| SCHEMBL5781064 | 0.79 | KDM4E (0.55) | PRKCIKDM4EALDH1A1GAAMAPT | |
| SCHEMBL7015318 | 0.79 | ALDH1A1 (0.48) | PRKCIPDE5AKDM4EALDH1A1MAPT | |
| SCHEMBL7008203 | 0.79 | KDM4E (0.48) | PRKCIPDE5AKDM4EALDH1A1MAPT | |
| SCHEMBL7017308 | 0.78 | PRKCI (0.50) | PRKCIPDE5AKDM4EALDH1A1MAPT | |
| SCHEMBL7169927 | 0.78 | KDM4E (0.50) | PRKCIKDM4EALDH1A1GAAMAPT | |
| SCHEMBL5130031 | 0.78 | SMN1; SMN2 (0.46) | PRKCIPDE5AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323719-A1 | Thienopyrimidine compounds and salts thereof and process for the preparation of the same | NIPPON SODA CO., LTD. (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6482948-B1 | Thienopyrimidine compounds and salts thereof and process for the preparation of the same | NIPPON SODA CO., LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| EP-1167367-A1 | THIENOPYRIMIDINE COMPOUNDS AND SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | NIPPON SODA CO., LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |