SCHEMBL719871

SCHEMBL719871

O=C(O)c1ccc2c(C(=O)O)c1CCCCC2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 4/20 0.46
ALDH1A1 P00352 4/20 0.39
RXRA P19793 4/20 0.39
RXRB P28702 3/20 0.39
RXRG P48443 3/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
GFER P55789 1/20 0.37
BCL2L1 Q07817 1/20 0.37
BAD Q92934 1/20 0.37
CYP1A2 P05177 1/20 0.37
MEN1 O00255 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
KMT2A Q03164 2/20 0.36
CXCR5 P32302 1/20 0.36
XDH P47989 1/20 0.36
SLC22A12 Q96S37 1/20 0.36
CXCR2 P25025 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL720289 1.00 METAP2 (0.46) METAP2ALDH1A1RXRARXRBRXRG
SCHEMBL564223 0.98 METAP2 (0.47) METAP2ALDH1A1RXRARXRBRXRG
SCHEMBL3658748 0.94 ALDH1A1 (0.44) METAP2ALDH1A1RXRARXRBRXRG
SCHEMBL970697 0.93 ALDH1A1 (0.43) METAP2ALDH1A1RXRARXRBRXRG
Terephthalic Acid SCHEMBL5393223 0.91 ALDH1A1 (0.47) METAP2ALDH1A1RXRARXRBRXRG
Cyclohexane SCHEMBL5999616 0.91 CYP1A2 (0.38) METAP2ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL196225 0.86 CYP1A2 (0.41) METAP2ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL967549 0.85 CYP1A2 (0.44) METAP2ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL819226 0.85 METAP2 (0.51) METAP2ALDH1A1RXRARXRBRXRG
SCHEMBL3091854 0.82 CYP1A2 (0.55) ALDH1A1RXRARXRBRXRGKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2267547-B1 Toner comprising purified polyester resins and production method thereof XEROX CORP (US) 2014-02-26 EP claimed
US-8293444-B2 Purified polyester resins for toner performance improvement XEROX CORPORATION (US) 2012-10-23 US claimed
US-20100330485-A1 PURIFIED POLYESTER RESINS FOR TONER PERFORMANCE IMPROVEMENT XEROX CORPORATION (US) 2010-12-30 US claimed
EP-2267547-A1 Toner comprising purified polyester resins and production method thereof Xerox Corporation (US) 2010-12-29 EP claimed
US-11815851-B2 Toner compositions and additives XEROX CORPORATION (US) 2023-11-14 US disclosed
EP-4266124-A1 TONER COMPOSITION Xerox Corporation (US) 2023-10-25 EP disclosed
US-20230333495-A1 Toner Composition U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2023-10-19 US disclosed
US-20230324824-A1 Toner Comprising Charge Control Agent U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2023-10-12 US disclosed
US-20230296997-A1 Toner Comprising Reactive Charge Control Agent U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2023-09-21 US disclosed
US-20230296998-A1 Toner Comprising Charge Control Agent U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2023-09-21 US disclosed
EP-4246238-A1 TONER COMPRISING REACTIVE CHARGE CONTROL AGENT Xerox Corporation (US) 2023-09-20 EP disclosed
EP-4246233-A1 TONER COMPRISING CHARGE CONTROL AGENT Xerox Corporation (US) 2023-09-20 EP disclosed
US-20110207044-A1 TUNABLE GLOSS TONERS XEROX CORPORATION (US) 2011-08-25 US disclosed
US-20110206400-A1 ELECTROPHOTOGRAPHIC APPARATUS XEROX CORPORATION (US) 2011-08-25 US disclosed
US-20110177444-A1 ADDITIVE PACKAGE FOR TONER XEROX CORPORATION (US) 2011-07-21 US disclosed
US-20110086301-A1 EMULSION AGGREGATION TONER COMPOSITION XEROX CORPORATION (US) 2011-04-14 US disclosed
US-20100330486-A1 Toner Compositions XEROX CORPORATION (US) 2010-12-30 US disclosed
US-20100330485-A1 PURIFIED POLYESTER RESINS FOR TONER PERFORMANCE IMPROVEMENT XEROX CORPORATION (US) 2010-12-30 US disclosed
EP-2267547-A1 Toner comprising purified polyester resins and production method thereof Xerox Corporation (US) 2010-12-29 EP disclosed
EP-2267545-A1 Toner compositions Xerox Corporation (US) 2010-12-29 EP disclosed