SCHEMBL7198979

SCHEMBL7198979

CCCCCC1CCCC2CCCC=C21

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 8/20 0.38
S1PR2 O95136 1/20 0.31
S1PR4 O95977 1/20 0.31
S1PR1 P21453 1/20 0.31
S1PR3 Q99500 1/20 0.31
S1PR5 Q9H228 1/20 0.31
CNR2 P34972 7/20 0.31
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10394276 0.92 CYP19A1 (0.39) CYP19A1CNR2EPHX1
SCHEMBL16825226 0.77
SCHEMBL16599750 0.73
SCHEMBL31239719 0.72
SCHEMBL23568278 0.70 CYP19A1 (0.38) CYP19A1EPHX1
SCHEMBL7640444 0.70 CYP1A2 (0.31)
SCHEMBL27446512 0.70 ALDH1A1 (0.31)
SCHEMBL28605156 0.69 NOS1 (0.38) CYP19A1
SCHEMBL3267370 0.69 CYP1A2 (0.43) CYP19A1S1PR2S1PR4S1PR1S1PR3
SCHEMBL31239801 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985651-B1 Process for obtaining mixtures of isomeric acyloctahydronaphthalenes MILLENNIUM SPECIALTY CHEM INC (US) 2003-10-22 EP disclosed
EP-0985651-B1 Process for obtaining mixtures of isomeric acyloctahydronaphthalenes MILLENNIUM SPECIALTY CHEM INC (US) 2003-10-22 EP disclosed
US-6160182-A Process for obtaining mixtures of isomeric acyloctahydronaphthalenes MILLENNIUM SPECIALTY CHEMICALS (US) 2000-12-12 US disclosed
US-6160182-A Process for obtaining mixtures of isomeric acyloctahydronaphthalenes MILLENNIUM SPECIALTY CHEMICALS (US) 2000-12-12 US disclosed
US-6160182-A Process for obtaining mixtures of isomeric acyloctahydronaphthalenes MILLENNIUM SPECIALTY CHEMICALS (US) 2000-12-12 US disclosed
EP-0985651-A1 Process for obtaining mixtures of isomeric acyloctahydronaphthalenes Millennium Specialty Chemicals, Inc. (US) 2000-03-15 EP disclosed
EP-0985651-A1 Process for obtaining mixtures of isomeric acyloctahydronaphthalenes Millennium Specialty Chemicals, Inc. (US) 2000-03-15 EP disclosed
EP-0985651-A1 Process for obtaining mixtures of isomeric acyloctahydronaphthalenes Millennium Specialty Chemicals, Inc. (US) 2000-03-15 EP disclosed