Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 8/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203259 | 0.94 | ITGB1 (0.36) | BACE1FNTAFNTBPGGT1BCCR1 | |
| SCHEMBL7198903 | 0.91 | CTSL (0.39) | BACE1CCR1 | |
| SCHEMBL7201997 | 0.85 | BACE1 (0.35) | CCKBRBACE1CCR1 | |
| SCHEMBL7197725 | 0.84 | ITGB1 (0.41) | BACE1CCR1 | |
| SCHEMBL7199086 | 0.84 | ITGB1 (0.40) | BACE1CCR1 | |
| SCHEMBL7200493 | 0.82 | ITGB1 (0.43) | BACE1CCR1 | |
| SCHEMBL7197381 | 0.80 | ITGB1 (0.41) | BACE1CCR1 | |
| SCHEMBL7198890 | 0.79 | CTSL (0.38) | BACE1 | |
| SCHEMBL7196140 | 0.77 | ITGB1 (0.38) | BACE1 | |
| SCHEMBL7201999 | 0.75 | CTSL (0.38) | BACE1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596687-B1 | For treatment of many inflammatory and autoimmune diseases | BIOGEN, INC. | 2003-07-22 | — | — | US | claimed |