Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2971191 | 0.79 | NPC1 (0.34) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL2972410 | 0.79 | HTT (0.38) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL4633219 | 0.69 | TYR (0.50) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL30044969 | 0.69 | TYR (0.50) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL4632556 | 0.67 | HTT (0.46) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL4633204 | 0.66 | NPC1 (0.48) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL819273 | 0.65 | LIPG (0.45) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL6413165 | 0.65 | CTRC (0.43) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL11682168 | 0.65 | TYR (0.50) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL28184330 | 0.64 | SKP2 (0.44) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2481760-B1 | INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME | CHINA PETROLEUM & CHEM CORP (CN) | 2021-05-05 | — | — | EP | claimed |
| EP-0963761-B1 | Biomedical devices with hydrophilic coatings | JOHNSON & JOHNSON VISION CARE (US) | 2003-10-29 | — | — | EP | claimed |
| EP-3271368-B1 | NOVEL PHOSPHINANE AND AZAPHOSPHINANE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2018-10-31 | — | — | EP | disclosed |
| EP-3271368-A1 | NOVEL PHOSPHINANE AND AZAPHOSPHINANE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2018-01-24 | — | — | EP | disclosed |
| WO-2017121969-A1 | NOVEL PHOSPHINANE AND AZAPHOSPHINANE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2017-07-20 | — | — | WO | disclosed |