Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27182290 | 0.85 | MAP2K7 (0.30) | — | |
| Hydrochloric Acid SCHEMBL27182257 | 0.82 | — | — | |
| Iodide SCHEMBL27182250 | 0.81 | MAP2K7 (0.30) | — | |
| Fluoride Ion SCHEMBL27182220 | 0.81 | MAP2K7 (0.30) | — | |
| Bromide SCHEMBL27203207 | 0.81 | MAP2K7 (0.30) | — | |
| Bromide SCHEMBL27182244 | 0.79 | — | — | |
| Fluoride Ion SCHEMBL27182271 | 0.79 | — | — | |
| Iodide SCHEMBL27182284 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL30338176 | 0.77 | GPR3 (0.34) | GPR3HTR2A | |
| Hydrochloric Acid SCHEMBL29912111 | 0.77 | GPR3 (0.34) | GPR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776909-B1 | HIGH DENSITY ETHYLENE POLYMER AND METHOD FOR PRODUCING THE SAME | ASAHI CHEMICAL IND (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1071690-A1 | METALLOCENE PURIFICATION PROCESS | ALBEMARLE CORPORATION (US) | 2001-01-31 | — | — | EP | disclosed |
| US-5973083-A | HIGH IMPACT RESISTANCE AND HIGH STIFFNESS, EXCELLENT MOLDABILITY, HIGH MELT FLOWABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1999-10-26 | — | — | US | disclosed |
| WO-1999052919-A1 | METALLOCENE PURIFICATION PROCESS | ALBEMARLE CORPORATION (US) | 1999-10-21 | — | — | WO | disclosed |
| EP-0776909-A1 | HIGH-DENSITY ETHYLENIC POLYMER AND PROCESS FOR PRODUCING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-06-04 | — | — | EP | disclosed |