Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 5/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD5 | P21918 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19749725 | 0.93 | DRD2 (0.72) | DRD2HRH3ACHEDRD3KCNH2 | |
| SCHEMBL19749829 | 0.86 | ALDH1A1 (0.54) | DRD2DRD3KDM2BDRD1DRD4 | |
| SCHEMBL15740669 | 0.86 | DRD2 (0.56) | DRD2HRH3ACHEDRD3DRD1 | |
| SCHEMBL7353948 | 0.85 | DRD2 (0.86) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL10834383 | 0.85 | DRD2 (0.61) | DRD2HRH3ACHEDRD3KCNH2 | |
| SCHEMBL18937874 | 0.84 | DRD4 (0.67) | DRD2DRD3DRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL7316558 | 0.84 | DRD2 (0.84) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL7315588 | 0.84 | DRD2 (0.84) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL15749492 | 0.83 | DRD2 (0.49) | DRD2ACHEDRD3DRD1DRD4 | |
| SCHEMBL15740644 | 0.83 | DRD2 (0.49) | DRD2ACHEDRD3DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850206-B2 | S1P and/or ATX modulating agents | BIOGEN MA INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-6596724-B2 | Used in promoting weight loss and treating eating disorders | BRISTOL-MYERS SQUIBB COMPANY | 2003-07-22 | — | — | US | disclosed |