Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK33 | Q9BYT3 | 11/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710352 | 0.89 | MAPT (0.42) | POLBTDP1KMT2AMEN1KDM4E | |
| SCHEMBL6710252 | 0.89 | STK33 (0.37) | STK33POLBTDP1KMT2AMEN1 | |
| SCHEMBL6711798 | 0.88 | GPR35 (0.44) | STK33POLBTDP1KMT2AMEN1 | |
| SCHEMBL6710126 | 0.88 | STK33 (0.52) | STK33POLBTDP1KMT2AMEN1 | |
| SCHEMBL6708854 | 0.88 | KMT2A (0.42) | STK33KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6711762 | 0.88 | MAP3K5 (0.41) | POLBTDP1KMT2AALDH1A1LMNA | |
| SCHEMBL6713406 | 0.87 | NPC1 (0.41) | LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6710055 | 0.87 | IRAK4 (0.41) | KMT2AMEN1ALDH1A1NPC1CYP1A2 | |
| SCHEMBL6711406 | 0.86 | GRIK1 (0.38) | TDP1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6707774 | 0.86 | TDP1 (0.44) | TDP1KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |