Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CD44 | P16070 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | PNMT | P11086 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.33 |
| ▸ | IKBKB | O14920 | 2/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28779140 | 0.98 | LMNA (0.39) | LMNAKMT2AMEN1THRBBLM | |
| Hydrochloric Acid SCHEMBL29951826 | 0.98 | LMNA (0.39) | LMNAKMT2AMEN1THRBBLM | |
| Hydrochloric Acid SCHEMBL29168703 | 0.98 | LMNA (0.39) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL10974814 | 0.84 | PRCP (0.41) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL2553918 | 0.83 | CD44 (0.56) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL29935954 | 0.83 | CD44 (0.56) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL19708906 | 0.83 | PNMT (0.56) | CD44PNMTMAOBPRCP | |
| Hydrochloric Acid SCHEMBL14686001 | 0.82 | CD44 (0.54) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL629055 | 0.80 | CD44 (0.39) | CD44PNMTALDH1A1OXTRDYRK2 | |
| SCHEMBL27523831 | 0.72 | MEN1 (0.37) | LMNAKMT2AMEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002165-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2023-01-26 | — | — | WO | disclosed |
| EP-1363900-A1 | ISOINDOLE-IMIDE COMPOUNDS AS TNF-INHIBITORS | CELGENE CORPORATION (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002059106-A1 | ISOINDOLE-IMIDE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | CELGENE CORPORATION (US) | 2002-08-01 | — | — | WO | disclosed |