Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | DRD4 | P21917 | 5/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CCL2 | P13500 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7196330 | 0.96 | DRD2 (0.38) | DRD2DRD4BRD4CCL2CYP19A1 | |
| SCHEMBL29458545 | 0.74 | DRD2 (0.41) | DRD2DRD4BRD4CCL2CYP19A1 | |
| SCHEMBL251288 | 0.74 | DRD2 (0.41) | DRD2DRD4BRD4CCL2CYP19A1 | |
| SCHEMBL30186426 | 0.73 | DRD2 (0.40) | DRD2DRD4BRD4CCL2CYP19A1 | |
| SCHEMBL9148106 | 0.73 | DRD2 (0.40) | DRD2DRD4BRD4CCL2CYP19A1 | |
| SCHEMBL9148116 | 0.73 | DRD2 (0.40) | DRD2DRD4BRD4CCL2CYP19A1 | |
| SCHEMBL29959900 | 0.73 | DRD2 (0.40) | DRD2DRD4BRD4CCL2CYP19A1 | |
| Lithium SCHEMBL9145416 | 0.73 | DRD2 (0.40) | DRD2DRD4BRD4CCL2CYP19A1 | |
| SCHEMBL5574454 | 0.73 | DRD2 (0.40) | DRD2DRD4BRD4CCL2CYP19A1 | |
| SCHEMBL813597 | 0.73 | DRD2 (0.40) | DRD2DRD4BRD4CCL2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668865-B1 | INDENYL COMPOUNDS AND CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | DSM NV (NL) | 2003-07-23 | — | — | EP | disclosed |
| US-5990253-A | METALLOCENES HAVING THE INDENE RING BINDING AT THE 2-POSITION RATHER THAN AT THE 1-POSITION; COORDINATION CATALYSTS; LESS CRYSTALLIZATION IN THE ADDITION POLYMERIZATION OF ELASTOMERS | DSM N.V. (NL) | 1999-11-23 | — | — | US | disclosed |
| US-5646322-A | Indenyl compounds and catalyst components for the polymerization of olefins | DSM N.V. (NL) | 1997-07-08 | — | — | US | disclosed |
| EP-0668865-A1 | INDENYL COMPOUNDS AND CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | DSM N.V. (NL) | 1995-08-30 | — | — | EP | disclosed |
| WO-1994011406-A1 | INDENYL COMPOUNDS AND CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | DSM N.V. (NL) | 1994-05-26 | — | — | WO | disclosed |