Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959107 | 0.94 | ALDH1A1 (0.47) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6959053 | 0.90 | ALDH1A1 (0.45) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6667428 | 0.90 | ALDH1A1 (0.51) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6964935 | 0.89 | ALDH1A1 (0.44) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6957798 | 0.86 | ALDH1A1 (0.45) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6958785 | 0.85 | ALDH1A1 (0.46) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6958938 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6673044 | 0.85 | ALDH1A1 (0.61) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6959857 | 0.84 | ALDH1A1 (0.45) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6961431 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HPGDGAAKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292575-A2 | 1-ARYL-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001098275-A2 | 1-ARYL-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-12-27 | — | — | WO | disclosed |