SCHEMBL7199863

SCHEMBL7199863

O=Cc1ccccc1C(=O)NNO

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
LMNA P02545 1/20 0.46
THRB P10828 1/20 0.46
BLM P54132 1/20 0.46
POLB P06746 1/20 0.44
TRIM24 O15164 1/20 0.43
TRIM33 Q9UPN9 1/20 0.43
KDM4E B2RXH2 3/20 0.39
MPO P05164 1/20 0.39
GAA P10253 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HIF1A Q16665 1/20 0.39
CAPN1 P07384 1/20 0.39
ALDH1A1 P00352 2/20 0.39
SRC P12931 1/20 0.39
TSHR P16473 1/20 0.39
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7542943 0.86 GAA (0.55) MEN1KMT2ATDP1LMNATHRB
SCHEMBL28257495 0.82 CA1 (0.62) MEN1KMT2ATDP1LMNATHRB
SCHEMBL9825116 0.82 CA1 (0.62) MEN1KMT2ATDP1LMNATHRB
SCHEMBL1932685 0.82 MEN1 (0.48) MEN1KMT2ATDP1LMNATHRB
SCHEMBL8602780 0.80 KMT2A (0.39) MEN1KMT2ATDP1LMNATHRB
SCHEMBL6328702 0.80 CTSD (0.50) MEN1KMT2ATDP1LMNATHRB
SCHEMBL3419592 0.80 MEN1 (0.46) MEN1KMT2ATDP1LMNATHRB
SCHEMBL5350192 0.80 MEN1 (0.46) MEN1KMT2ATDP1LMNATHRB
SCHEMBL728983 0.80 GAA (0.55) MEN1KMT2ATDP1LMNATHRB
SCHEMBL5350946 0.78 TDP1 (0.44) MEN1KMT2ATDP1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6537783-B1 DNA/RNA sequences, oligonucleotide primer, and DNA polymerase; can be used for fluorescent labeling BIO MERIEUX (FR) 2003-03-25 US disclosed