Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5477577 | 0.82 | CTSD (0.49) | CTSDCA1CA2CA9ALDH1A1 | |
| SCHEMBL11414557 | 0.82 | CTSD (0.53) | CTSDCA1CA2CA9ALDH1A1 | |
| SCHEMBL1932685 | 0.82 | MEN1 (0.48) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL7542943 | 0.82 | GAA (0.55) | CA1CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL10279067 | 0.81 | LMNA (0.43) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL14185996 | 0.80 | MAOB (0.47) | ALDH1A1MEN1KMT2ABLMMAOB | |
| SCHEMBL30547074 | 0.80 | CTSD (0.63) | CTSDCA1CA2CA9ALDH1A1 | |
| SCHEMBL239328 | 0.80 | CTSD (0.63) | CTSDCA1CA2CA9ALDH1A1 | |
| SCHEMBL3419592 | 0.80 | MEN1 (0.46) | CA1CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL7199863 | 0.80 | MEN1 (0.46) | CA1CA9ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221842-B2 | Bicyclic methylene aziridines and reactions thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-12-29 | — | — | US | disclosed |
| US-20080139560-A1 | Ion Channel Modulators | SCION PHARMACEUTICALS, INC. | 2008-06-12 | — | — | US | disclosed |
| US-20050075323-A1 | Beta3 adrenergic receptor agonists and uses thereof | PFIZER INC | 2005-04-07 | — | — | US | disclosed |
| US-6706743-B2 | β3 adrenergic receptor agonists and uses thereof | PFIZER INC | 2004-03-16 | — | — | US | disclosed |
| US-20030203913-A1 | Beta3 adrenergic receptor agonists and uses thereof | PFIZER INC. | 2003-10-30 | — | — | US | disclosed |
| EP-1326861-A1 | ALPHA-ARYL ETHANOLAMINES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | Pfizer Products Inc. (US) | 2003-07-16 | — | — | EP | disclosed |
| US-6566377-B2 | β3 adrenergic receptor agonists and uses thereof | PFIZER INC. | 2003-05-20 | — | — | US | disclosed |
| US-20020094993-A1 | Compositions for repelling crawling insects | S.C. JOHNSON & SON, INC. | 2002-07-18 | — | — | US | disclosed |
| EP-0527517-B1 | Photographic direct positive material containing a masked benzotriazole stabilizer | AGFA GEVAERT (BE) | 2002-07-03 | — | — | EP | disclosed |
| US-20020052392-A1 | Bita3 adrenergic receptor agonists and uses thereof | DAY ROBERT F (US) | 2002-05-02 | — | — | US | disclosed |
| US-5254443-A | Photographic direct positive material containing a masked benzotriazole stabilizer | AGFA-GEVAERT, N.V. (BE) | 1993-10-19 | — | — | US | disclosed |
| US-5190974-A | Analgesics | ROUSSEL UCLAF (FR) | 1993-03-02 | — | — | US | disclosed |
| EP-0527517-A1 | Photographic direct positive material containing a masked benzotriazole stabilizer | AGFA-GEVAERT N.V. (BE) | 1993-02-17 | — | — | EP | disclosed |
| EP-0496127-A1 | A negative type lithographic printing plate based on silver salt diffusion transfer | AGFA-GEVAERT N.V. (BE) | 1992-07-29 | — | — | EP | disclosed |
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0481562-A1 | A negative type lithographic printing plate | AGFA-GEVAERT N.V. (BE) | 1992-04-22 | — | — | EP | disclosed |
| EP-0473209-A1 | Method of making direct-positive computer output images | AGFA-GEVAERT N.V. (BE) | 1992-03-04 | — | — | EP | disclosed |
| EP-0465369-A1 | N-substituted derivatives of alpha-mercapto alkylamines, process for their preparation and intermediates obtained, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1992-01-08 | — | — | EP | disclosed |
| US-4358528-A | Formation of black-and-white silver-containing negative images by a diffusion transfer process | FUJI PHOTO FILM CO., LTD. (JP) | 1982-11-09 | — | — | US | disclosed |
| US-4309499-A | PROCESSING WITH ONE SOLUTION CONTAINING FOGGING AGENT, FOG PROMOTER, DEVELOPER, AND SOLVENT FOR SILVER HALIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1982-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203913-A1 | Beta3 adrenergic receptor agonists and uses thereof | ADRB3, ADRB1, ADRB2 | CTSD 4059/4885CA1 4180/4885CA2 2428/4885 |
| US-20050075323-A1 | Beta3 adrenergic receptor agonists and uses thereof | ADRB3, ADRB1, ADRB2 | CTSD 4018/4885CA1 4497/4885CA2 2810/4885 |
| US-20080139560-A1 | Ion Channel Modulators | CACNA1B, CACNA1C, TRPV1 | CTSD 2337/4885CA1 869/4885CA2 183/4885 |
| US-20020052392-A1 | Bita3 adrenergic receptor agonists and uses thereof | ADRB3, ADRA1A, ADRB1 | CTSD 4073/4885CA1 4537/4885CA2 3005/4885 |
| US-20020094993-A1 | Compositions for repelling crawling insects | ACHE, DDT, GAP43 | CTSD 836/4885CA1 1889/4885CA2 1428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.