Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18289504 | 1.00 | CES2 (0.44) | CES2CES1MAPTL3MBTL1GAA | |
| SCHEMBL9962627 | 0.90 | MAPT (0.45) | MAPTL3MBTL1GAAALDH1A1HPGD | |
| SCHEMBL18289506 | 0.89 | CES2 (0.43) | CES2CES1MAPTL3MBTL1GAA | |
| SCHEMBL9112717 | 0.89 | ALDH1A1 (0.46) | CES2CES1MAPTL3MBTL1GAA | |
| SCHEMBL13541031 | 0.86 | CES2 (0.42) | CES2CES1MAPTL3MBTL1GAA | |
| SCHEMBL103376 | 0.86 | CES2 (0.48) | CES2CES1MAPTALDH1A1HPGD | |
| SCHEMBL12021972 | 0.86 | CES2 (0.48) | CES2CES1MAPTALDH1A1HPGD | |
| SCHEMBL22729193 | 0.86 | CES2 (0.48) | CES2CES1MAPTALDH1A1HPGD | |
| SCHEMBL3085331 | 0.86 | CES2 (0.48) | CES2CES1MAPTALDH1A1HPGD | |
| SCHEMBL92006 | 0.86 | CES2 (0.48) | CES2CES1MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596445-B1 | Initiators for photopolymerization of radically polymerizable compounds | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-22 | — | — | US | disclosed |