Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930750 | 0.85 | CA2 (0.63) | CA2CA1MAPK1SLC1A2SLC1A1 | |
| SCHEMBL28017576 | 0.82 | CA2 (0.53) | CA2CA1MAPK1SLC1A2SLC1A1 | |
| SCHEMBL14125930 | 0.81 | CA2 (0.61) | CA2CA1MAPK1SLC1A2SLC1A1 | |
| SCHEMBL465030 | 0.77 | CA2 (0.70) | CA2CA1MAPK1SLC1A2SLC1A1 | |
| SCHEMBL27684610 | 0.77 | CA2 (0.56) | CA2CA1MAPK1SLC1A2SLC1A1 | |
| SCHEMBL11166941 | 0.77 | CA2 (0.61) | CA2CA1MAPK1SLC1A2SLC1A1 | |
| SCHEMBL819983 | 0.76 | CA2 (0.40) | CA2CA1MAPK1SLC1A2SLC1A1 | |
| SCHEMBL888504 | 0.76 | CA2 (0.56) | CA2CA1MAPK1SLC1A2SLC1A1 | |
| SCHEMBL13477875 | 0.75 | CA2 (0.61) | CA2CA1MAPK1SLC1A2SLC1A1 | |
| SCHEMBL25380887 | 0.75 | CA2 (0.41) | CA2CA1MAPK1SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030147973-A1 | The use of extracts and compounds derived from the plant Aristolochia taliscana and their analogues in the treatment of AIDS. | ACHENBACH HANS (DE) | 2003-08-07 | — | — | US | disclosed |
| US-20020099086-A1 | Use of extracts from aristolochia in the treatment of AIDS | PROTEOME SCIENCES PLC | 2002-07-25 | — | — | US | disclosed |
| EP-1027344-A2 | PHARMACEUTICAL COMPOUNDS ISOLATED FROM ARISTOLOCHIA TALISCANA | PROTEOME SCIENCES PLC (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999006388-A2 | PHARMACEUTICAL COMPOUNDS ISOLATED FROM ARISTOLOCHIA TALISCANA | PROTEOME SCIENCES PLC. (GB) | 1999-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099086-A1 | Use of extracts from aristolochia in the treatment of AIDS | ATL3, APRT, LSS | CA2 3931/4885CA1 3815/4885MAPK1 3068/4885 |
| US-20030147973-A1 | The use of extracts and compounds derived from the plant Aristolochia taliscana and their analogues in the treatment of AIDS. | ATL3, ERG28, LSS | CA2 4234/4885CA1 3938/4885MAPK1 2453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.