Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.34 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195728 | 0.91 | CYP1A2 (0.38) | CYP3A4CYP1A2CYP2D6CYP2C19AGBL2 | |
| SCHEMBL7197594 | 0.85 | MRGPRX4 (0.39) | CYP3A4CYP1A2CYP2D6CYP2C19MRGPRX4 | |
| SCHEMBL6488962 | 0.84 | MRGPRX4 (0.41) | CYP3A4CYP1A2CYP2D6CYP2C19MRGPRX4 | |
| SCHEMBL7199966 | 0.83 | CYP1A2 (0.38) | CYP3A4CYP1A2CYP2D6CYP2C19AGBL2 | |
| SCHEMBL6490617 | 0.82 | DCTPP1 (0.43) | CYP3A4CYP1A2CYP2D6CYP2C19MRGPRX4 | |
| SCHEMBL7192311 | 0.82 | CYP1A2 (0.38) | CYP3A4CYP1A2CYP2D6CYP2C19MRGPRX4 | |
| SCHEMBL6502236 | 0.81 | MRGPRX4 (0.39) | CYP3A4CYP1A2CYP2D6CYP2C19MRGPRX4 | |
| SCHEMBL6488927 | 0.80 | MRGPRX4 (0.44) | CYP3A4CYP1A2CYP2D6CYP2C19MRGPRX4 | |
| SCHEMBL6490408 | 0.80 | JMJD6 (0.41) | CYP3A4CYP1A2CYP2D6CYP2C19MEN1 | |
| SCHEMBL6489988 | 0.79 | DCTPP1 (0.40) | CYP3A4CYP1A2CYP2D6CYP2C19MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |