Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490031 | 0.90 | MEN1 (0.37) | MRGPRX4CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7199966 | 0.86 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2D6CYP2C19GLA | |
| SCHEMBL6488927 | 0.86 | MRGPRX4 (0.44) | MRGPRX4CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6488962 | 0.85 | MRGPRX4 (0.41) | MRGPRX4CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6490617 | 0.84 | DCTPP1 (0.43) | MRGPRX4CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6491606 | 0.84 | MRGPRX4 (0.41) | MRGPRX4CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7195728 | 0.83 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2D6CYP2C19GLA | |
| SCHEMBL7200308 | 0.81 | CYP3A4 (0.37) | MRGPRX4CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6489988 | 0.80 | DCTPP1 (0.40) | MRGPRX4CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6490408 | 0.79 | JMJD6 (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | MRGPRX4 2443/4885CYP1A2 247/4885CYP3A4 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.