Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 7/20 | 0.87 |
| ▸ | PAX8 | Q06710 | 5/20 | 0.85 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.85 |
| ▸ | MEN1 | O00255 | 9/20 | 0.85 |
| ▸ | THRB | P10828 | 9/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.85 |
| ▸ | BLM | P54132 | 8/20 | 0.85 |
| ▸ | RECQL | P46063 | 7/20 | 0.85 |
| ▸ | BRCA1 | P38398 | 6/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.85 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.85 |
| ▸ | MAPT | P10636 | 6/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.85 |
| ▸ | USP2 | O75604 | 4/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.85 |
| ▸ | TOP2A | P11388 | 4/20 | 0.85 |
| ▸ | HTT | P42858 | 4/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.85 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24711207 | 0.93 | S100A4 (1.00) | S100A4PAX8HSP90AA1MEN1THRB | |
| SCHEMBL13563882 | 0.93 | S100A4 (0.89) | S100A4PAX8HSP90AA1MEN1THRB | |
| SCHEMBL14562338 | 0.93 | S100A4 (0.89) | S100A4PAX8HSP90AA1MEN1THRB | |
| SCHEMBL13524758 | 0.93 | S100A4 (0.89) | S100A4PAX8HSP90AA1MEN1THRB | |
| SCHEMBL3036863 | 0.92 | S100A4 (0.86) | S100A4PAX8HSP90AA1MEN1THRB | |
| SCHEMBL8639928 | 0.92 | S100A4 (1.00) | S100A4PAX8HSP90AA1MEN1THRB | |
| SCHEMBL29338082 | 0.92 | S100A4 (1.00) | S100A4PAX8HSP90AA1MEN1THRB | |
| Daunorubicin SCHEMBL12864552 | 0.92 | MEN1 (1.00) | S100A4PAX8HSP90AA1MEN1THRB | |
| Daunorubicin SCHEMBL319903 | 0.92 | MEN1 (1.00) | S100A4PAX8HSP90AA1MEN1THRB | |
| Daunorubicin SCHEMBL13840952 | 0.92 | MEN1 (1.00) | S100A4PAX8HSP90AA1MEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995015983-A1 | PROCESS FOR IMMOBILISING BIOMOLECULES AND AFFINITY LIGANDS ON POLYMER CARRIERS | GLUESENKAMP KARL HEINZ (DE) | 1995-06-15 | — | — | WO | claimed |
| US-6602692-B1 | Reacting a water insoluble matrix having amino groups such as membranes, resins, microtiter plates, with an activating cyclobutene such as 1,2-diethoxycyclobut-1-en-3,4-dione and then incubating with an amino-functional protein | GLUESENKAMP KARL-HEINZ (DE) | 2003-08-05 | — | — | US | disclosed |