Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | BRD2 | P25440 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200545 | 0.84 | KDM4E (0.71) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL7202472 | 0.73 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL13154959 | 0.72 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL4504119 | 0.69 | ALDH1A1 (0.67) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL8199240 | 0.68 | BRD4 (0.61) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL14072010 | 0.67 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL12922681 | 0.67 | F10 (0.49) | KDM4EALDH1A1HSD17B10GAATSHR | |
| SCHEMBL8108086 | 0.67 | ALDH1A1 (0.47) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL7199531 | 0.67 | RXFP1 (0.52) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL3916185 | 0.66 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323719-A1 | Thienopyrimidine compounds and salts thereof and process for the preparation of the same | NIPPON SODA CO., LTD. (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6482948-B1 | Thienopyrimidine compounds and salts thereof and process for the preparation of the same | NIPPON SODA CO., LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| EP-1167367-A1 | THIENOPYRIMIDINE COMPOUNDS AND SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | NIPPON SODA CO., LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |