Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | WEE1 | P30291 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199532 | 0.86 | KDM4E (0.58) | RXFP1KDM4EWEE1PKMALDH1A1 | |
| SCHEMBL7196501 | 0.78 | WEE1 (0.51) | RXFP1KDM4EWEE1PKMALDH1A1 | |
| SCHEMBL7018701 | 0.75 | CDC7 (0.51) | RXFP1KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL7195650 | 0.68 | PRKCI (0.47) | KDM4EWEE1PKMALDH1A1MAPT | |
| SCHEMBL7200540 | 0.67 | KDM4E (0.49) | RXFP1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL3716439 | 0.67 | LMNA (0.67) | KDM4EALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL13367199 | 0.67 | PDE4D (0.54) | RXFP1KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL7007577 | 0.66 | ALDH1A1 (0.49) | RXFP1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL969115 | 0.66 | KDM4E (1.00) | RXFP1KDM4EWEE1PKMALDH1A1 | |
| SCHEMBL7017749 | 0.66 | CDC7 (0.46) | RXFP1KDM4EALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323719-A1 | Thienopyrimidine compounds and salts thereof and process for the preparation of the same | NIPPON SODA CO., LTD. (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6482948-B1 | Thienopyrimidine compounds and salts thereof and process for the preparation of the same | NIPPON SODA CO., LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| EP-1167367-A1 | THIENOPYRIMIDINE COMPOUNDS AND SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | NIPPON SODA CO., LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |