Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 16/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 15/20 | 0.59 |
| ▸ | AR | P10275 | 11/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197858 | 0.88 | PGR (0.56) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL4665348 | 0.88 | PGR (0.65) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL7148540 | 0.88 | PGR (0.65) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL7148546 | 0.88 | PGR (0.65) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL6453812 | 0.88 | PGR (0.65) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL7199834 | 0.85 | PGR (0.57) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL9019768 | 0.81 | PGR (0.68) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL9019815 | 0.80 | PGR (0.51) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8541351 | 0.79 | PGR (0.53) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8538261 | 0.79 | PGR (0.53) | PGRNR3C1ARCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596713-B1 | Antigestagenic, antiglucocorticoidal, antimineralcorticoidal or antiandrogenic effect | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-07-22 | — | — | US | disclosed |