SCHEMBL7200749

SCHEMBL7200749

Cc1cn(NC(=O)Cl)c(=O)[nH]c1=O

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.41
MAPK1 P28482 1/20 0.38
TK1 P04183 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8304489 0.78 MAPK1 (0.42) HPGDMAPK1TK1
SCHEMBL21284209 0.76 MAPK1 (0.43) HPGDMAPK1TK1
SCHEMBL25979517 0.74 MAPK1 (0.42) HPGDMAPK1TK1
SCHEMBL5353008 0.69 HPGD (0.55) HPGDMAPK1TK1
SCHEMBL10950422 0.68 MAPK1 (0.43) HPGDMAPK1TK1
SCHEMBL15688254 0.68 HPGD (0.50) HPGDMAPK1TK1
SCHEMBL7043681 0.67 MAPK1 (0.46) HPGDMAPK1TK1
SCHEMBL15538150 0.67 HPGD (0.45) HPGDMAPK1TK1
SCHEMBL6713750 0.67 MAPK1 (0.42) HPGDMAPK1TK1
SCHEMBL8741733 0.67 HPGD (0.53) HPGDMAPK1TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1310507-A2 Novel peptide nucleic acids NIELSEN, Peter Eigil (DK) 2003-05-14 EP disclosed
US-5773571-A BOND TO RNA AND DNA STRANDS NIELSEN PETER E (DK) 1998-06-30 US disclosed
US-5539082-A Peptide nucleic acids NIELSEN PETER E (DK) 1996-07-23 US disclosed
EP-0699208-A1 NOVEL PEPTIDE NUCLEIC ACIDS NIELSEN, Peter Eigil (DK) 1996-03-06 EP disclosed
WO-1994025477-A2 NOVEL PEPTIDE NUCLEIC ACIDS NIELSEN PETER E (DK) 1994-11-10 WO disclosed