Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TK1 | P04183 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21284209 | 0.82 | MAPK1 (0.43) | MAPK1HPGDTYMPALDH1A1LMNA | |
| SCHEMBL25979517 | 0.80 | MAPK1 (0.42) | MAPK1HPGDTYMPALDH1A1LMNA | |
| SCHEMBL7200749 | 0.78 | HPGD (0.41) | MAPK1HPGDTK1 | |
| SCHEMBL29138705 | 0.73 | MAPK1 (0.41) | MAPK1HPGDTYMPALDH1A1LMNA | |
| SCHEMBL15688254 | 0.73 | HPGD (0.50) | MAPK1HPGDTK1 | |
| SCHEMBL7043681 | 0.72 | MAPK1 (0.46) | MAPK1HPGDTYMPALDH1A1LMNA | |
| SCHEMBL16588800 | 0.72 | MAPK1 (0.40) | MAPK1HPGDTYMPALDH1A1LMNA | |
| SCHEMBL646139 | 0.70 | TDP1 (0.59) | MAPK1HPGDTYMPALDH1A1LMNA | |
| SCHEMBL16248 | 0.70 | MAPK1 (0.47) | MAPK1HPGDTYMPALDH1A1LMNA | |
| SCHEMBL6250948 | 0.70 | MAPK1 (0.38) | MAPK1HPGDALDH1A1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5969135-A | COMPOUNDS FOR USE AS ANTISENSE CONTROL OF GENE EXPRESSION AND HYBRIDIZATION | ICN PHARMACEUTICALS, INC. (US) | 1999-10-19 | — | — | US | disclosed |
| EP-0789707-A4 | AMINO ACID NUCLEIC ACIDS | ICN PHARMACEUTICALS (US) | 1999-02-24 | — | — | EP | disclosed |
| EP-0789707-A1 | AMINO ACID NUCLEIC ACIDS | ICN PHARMACEUTICALS (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996014330-A1 | AMINO ACID NUCLEIC ACIDS | ICNPHARMACEUTICALS (US) | 1996-05-17 | — | — | WO | disclosed |