Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TK1 | P04183 | 5/20 | 0.39 |
| ▸ | TYMP | P19971 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21284209 | 0.82 | MAPK1 (0.43) | MAPK1HPGDTK1TYMPALDH1A1 | |
| SCHEMBL8304489 | 0.80 | MAPK1 (0.42) | MAPK1HPGDTK1TYMPALDH1A1 | |
| SCHEMBL7200749 | 0.74 | HPGD (0.41) | MAPK1HPGDTK1 | |
| SCHEMBL646139 | 0.74 | TDP1 (0.59) | MAPK1HPGDTK1TYMPALDH1A1 | |
| SCHEMBL6250948 | 0.73 | MAPK1 (0.38) | MAPK1HPGDTK1ALDH1A1LMNA | |
| SCHEMBL15688254 | 0.73 | HPGD (0.50) | MAPK1HPGDTK1 | |
| SCHEMBL16588800 | 0.72 | MAPK1 (0.40) | MAPK1HPGDTK1TYMPALDH1A1 | |
| SCHEMBL16248 | 0.70 | MAPK1 (0.47) | MAPK1HPGDTK1TYMPALDH1A1 | |
| SCHEMBL5176789 | 0.68 | MAPK1 (0.46) | MAPK1HPGDTK1TYMPALDH1A1 | |
| SCHEMBL7141531 | 0.68 | MAPK1 (0.46) | MAPK1HPGDTK1TYMPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178230-A1 | PHOSPHORODIAMIDATE MORPHOLINO OLIGOMER CONJUGATES | SAREPTA THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| EP-4219717-A2 | EXON SKIPPING OLIGOMERS FOR MUSCULAR DYSTROPHY | Sarepta Therapeutics, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |