Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252667 | 1.00 | NOD1 (0.49) | NOD1MAPTSMN1; SMN2KDM4ETHRB | |
| SCHEMBL931570 | 1.00 | NOD1 (0.49) | NOD1MAPTSMN1; SMN2KDM4ETHRB | |
| SCHEMBL252666 | 1.00 | NOD1 (0.49) | NOD1MAPTSMN1; SMN2KDM4ETHRB | |
| SCHEMBL931571 | 1.00 | NOD1 (0.49) | NOD1MAPTSMN1; SMN2KDM4ETHRB | |
| SCHEMBL8612865 | 1.00 | NOD1 (0.49) | NOD1MAPTSMN1; SMN2KDM4ETHRB | |
| SCHEMBL25211227 | 1.00 | NOD1 (0.49) | NOD1MAPTSMN1; SMN2KDM4ETHRB | |
| SCHEMBL21243388 | 1.00 | NOD1 (0.49) | NOD1MAPTSMN1; SMN2KDM4ETHRB | |
| SCHEMBL21291888 | 1.00 | NOD1 (0.49) | NOD1MAPTSMN1; SMN2KDM4ETHRB | |
| SCHEMBL20553468 | 1.00 | NOD1 (0.49) | NOD1MAPTSMN1; SMN2KDM4ETHRB | |
| SCHEMBL5801833 | 1.00 | NOD1 (0.49) | NOD1MAPTSMN1; SMN2KDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030134420-A1 | Methods and compositions for gene delivery | IMMUNE RESPONSE CORPORATION, THE | 2003-07-17 | — | — | US | disclosed |
| WO-2001060415-A1 | METHODS AND COMPOSITIONS FOR GENE DELIVERY | THE IMMUNE RESPONSE CORPORATION (US) | 2001-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134420-A1 | Methods and compositions for gene delivery | POLRMT, NUP205, POLM | NOD1 3925/4885MAPT 2431/4885SMN1; SMN2 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.