Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198171 | 0.77 | ALDH1A1 (0.40) | ALDH1A1EPHX1SPHK1SPHK2GBA1 | |
| SCHEMBL6194532 | 0.77 | ALDH1A1 (0.40) | ALDH1A1EPHX1SPHK1SPHK2GBA1 | |
| SCHEMBL6194421 | 0.77 | ALDH1A1 (0.40) | ALDH1A1EPHX1SPHK1SPHK2GBA1 | |
| SCHEMBL6192081 | 0.77 | ALDH1A1 (0.40) | ALDH1A1EPHX1SPHK1SPHK2GBA1 | |
| SCHEMBL6193299 | 0.77 | ALDH1A1 (0.40) | ALDH1A1EPHX1SPHK1SPHK2GBA1 | |
| SCHEMBL6195417 | 0.77 | ALDH1A1 (0.40) | ALDH1A1EPHX1SPHK1SPHK2GBA1 | |
| SCHEMBL4395556 | 0.73 | ENPP2 (0.35) | ALDH1A1 | |
| SCHEMBL22236038 | 0.69 | USP2 (0.33) | ALDH1A1CYP1A2 | |
| SCHEMBL11219791 | 0.67 | ALDH1A1 (0.54) | ALDH1A1EPHX1SPHK1SPHK2GBA1 | |
| SCHEMBL20732767 | 0.67 | ALDH1A1 (0.54) | ALDH1A1EPHX1SPHK1SPHK2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003039523-A2 | OLIGONUCLEOTIDES MODIFIED WITH NOVEL α-L-RNA ANALOGUES | EXIQON A/S (DK) | 2003-05-15 | — | — | WO | disclosed |